Blood-brain barrier imaging
Blood-brain barrier (BBB) integrity is emerging as a critical determinant of brain health. BBB breakdown has been associated with multiple dementias, multiple sclerosis and stroke.
Understanding BBB integrity is a key focus in neurodegeneration research, both to ensure treatments are more effective, and to serve as a therapeutic target directly.
BBB imaging with multi-echo ASL
Working with leading imaging CROs such as Mediri, Quantified Imaging is one of the few companies in the world able to non-invasively measure BBB integrity. Combining our unique Bayesian inference software with 10 minutes of multi-echo ASL imaging, this new biomarker of neurodegeneration has already been demonstrated on a large multi-national study.
Texch image of BBB integrity for a healthy subject, acquired using multi-echo ASL on a Siemens 3T.
Dr Julia Müller, COO, Mediri GmbH
The gold standard in perfusion MRI //
// precision-guiding treatment// widening access to early diagnosis// improving trial endpoints// reducing contrast use// reducing radiation exposure
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