The Importance of Perfusion
Perfusion is the delivery of oxygen and nutrients to cells via blood flow and is fundamental to brain health. Disrupted perfusion is linked to a wide range of brain diseases, including dementia, traumatic brain injury, stroke and epilepsy. Importantly, disrupted perfusion is often an early marker of disease, emerging before more serious and non-reversible damage.
Perfusion Imaging via ASL
Arterial spin labelling (ASL) is a type of MRI scan that non-invasively measures brain perfusion. Unlike the existing standard of care (DSC-MRI and PET), ASL-MRI does not require the patient to be injected with toxic or radioactive compounds, which means it is safe to use on many more patients, including children.
ASL is available on all major MRI platforms, including GE, Siemens, and Philips. An ASL scan takes less than five minutes and, unlike traditional DSC perfusion and PET, is safe for use on almost all patients, including children and those with kidney disease.
Dynamic ASL image captures inflowing blood in the brain of a healthy subject, acquired on Siemens Vida 3T. ASL scans take 5 minutes and can be run on almost all GE, Siemens and Philips scanners.
Quantified Imaging’s ASL Solution
CBF (left) and ATT (right) maps generated from Siemens Vida 3T
Quantified Imaging produces software to quantify abnormalities in ASL scans, supporting diagnosis, disease monitoring and drug development.
Our software is compatible with ASL scans from all the major MRI manufacturers and is based on our world-leading Bayesian inference technology developed over 20 years at the Universities of Oxford and Nottingham.
Our software produces:
• Class-leading cerebral blood flow (CBF) and arterial transit time (ATT) maps
• CBF Z-scores, corrected for age, sex and BMI
We also provide advanced features for clinical trials.
Next-generation MRI analysis //
// accurate physiology assessment// reducing scan session time// aiding drug development// improving clinical practice// accelerating clinical trials
For further information or to arrange a demo, get in touch
